Sylvain Doré Selected Research

ONO 8713

1/2020	Effect of Experimental Ischemic Stroke and PGE2 EP1 Selective Antagonism in Alzheimer's Disease Mouse Models.
12/2008	Selective blockade of PGE2 EP1 receptor protects brain against experimental ischemia and excitotoxicity, and hippocampal slice cultures against oxygen-glucose deprivation.

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Sylvain Doré Research Topics

Disease

42	Stroke (Strokes) 02/2022 - 05/2003
27	Brain Ischemia (Cerebral Ischemia) 01/2021 - 09/2002
19	Brain Injuries (Brain Injury) 01/2020 - 12/2005
18	Ischemic Stroke 01/2022 - 08/2007
18	Ischemia 01/2020 - 06/2002
17	Gliosis 10/2020 - 11/2005
16	Infarction (Infarctions) 01/2020 - 07/2003
15	Cerebral Hemorrhage 08/2021 - 06/2006
13	Inflammation (Inflammations) 06/2021 - 05/2003
12	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 04/2022 - 07/2006
11	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2020 - 03/2007
11	Neuroinflammatory Diseases 01/2020 - 05/2003
11	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2002
8	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020 - 09/2011
5	Hemorrhage 08/2021 - 06/2006
5	Hematoma 01/2021 - 10/2013
5	Hemorrhagic Stroke 01/2021 - 09/2011
5	Nervous System Diseases (Neurological Disorders) 10/2020 - 12/2006
5	Wounds and Injuries (Trauma) 01/2020 - 10/2013
4	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2022 - 05/2003
3	Intracranial Vasospasm 01/2021 - 11/2014
3	Edema (Dropsy) 01/2020 - 01/2014
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 12/2013
2	Pain (Aches) 04/2022 - 06/2021
2	Sickle Cell Anemia (Hemoglobin S Disease) 01/2022 - 06/2021
2	Vitamin D Deficiency 01/2021 - 01/2021
2	Brain Edema (Cerebral Edema) 01/2020 - 01/2019
2	Hypoxia (Hypoxemia) 01/2018 - 01/2012
2	Aneurysm (Aneurysms) 01/2018 - 01/2018
2	Neurologic Manifestations (Neurological Manifestations) 10/2012 - 12/2010
2	Memory Disorders (Memory Loss) 09/2012 - 01/2008
2	Brain Infarction 12/2010 - 08/2010
2	Transient Ischemic Attack 09/2010 - 01/2005
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 09/2021
1	Coma (Comas) 08/2021
1	Acute Kidney Injury (Acute Renal Failure) 06/2021
1	Pulmonary Hypertension 06/2021
1	Hemolysis 06/2021
1	Hemoglobinopathies 06/2021
1	Neoplasms (Cancer) 01/2021

Drug/Important Bio-Agent (IBA)

22	ProstaglandinsIBA 01/2020 - 05/2003
12	Heme (Haem)IBA 06/2021 - 09/2002
12	Dinoprostone (PGE2)FDA Link 01/2020 - 12/2008
10	IronIBA 01/2020 - 05/2015
9	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 06/2006
8	Proteins (Proteins, Gene)FDA Link 06/2021 - 03/2008
7	HaptoglobinsIBA 01/2022 - 01/2015
7	Heme Oxygenase-1IBA 01/2018 - 09/2002
6	Hemoglobins (Hemoglobin)IBA 06/2021 - 01/2016
6	Prostaglandins EIBA 01/2018 - 12/2006
6	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2015 - 08/2003
6	Neuroprotective AgentsIBA 10/2013 - 05/2003
6	EnzymesIBA 07/2010 - 06/2002
5	CytokinesIBA 01/2021 - 05/2007
5	Carbon MonoxideIBA 11/2019 - 02/2009
4	Oxygen (Dioxygen)IBA 01/2022 - 12/2008
4	HemopexinIBA 06/2021 - 05/2009
4	Biomarkers (Surrogate Marker)IBA 06/2021 - 01/2018
4	AntioxidantsIBA 10/2020 - 06/2002
4	salicylhydroxamic acid (SHAM)IBA 01/2020 - 10/2013
4	prostaglandin F2alpha receptorIBA 01/2018 - 01/2009
4	Free RadicalsIBA 03/2008 - 09/2002
4	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 06/2007 - 06/2002
3	BilirubinIBA 08/2021 - 09/2013
3	Vitamin D FDA LinkGeneric 01/2021 - 01/2020
3	Hemin (Panhematin)FDA Link 01/2020 - 06/2006
3	GasesIBA 01/2019 - 08/2007
3	ChemokinesIBA 01/2019 - 05/2007
3	heme oxygenase-2IBA 02/2016 - 07/2003
3	Catechin (Z 7300)IBA 03/2015 - 12/2010
3	ResveratrolIBA 08/2013 - 01/2005
3	N-Methylaspartate (NMDA)IBA 09/2010 - 12/2008
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 06/2010 - 09/2006
2	Aquaporin 4IBA 10/2020 - 08/2019
2	Transcription Factors (Transcription Factor)IBA 10/2020 - 03/2015
2	Aquaporins (Water Channels)IBA 10/2020 - 07/2018
2	Dimethyl FumarateIBA 01/2020 - 01/2019
2	ONO 8713IBA 01/2020 - 12/2008
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2018
2	Glutamic Acid (Glutamate)FDA Link 01/2019 - 03/2008
2	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 12/2015
2	SC 51089IBA 12/2015 - 01/2014
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 03/2015 - 01/2014
2	diazonaphthalenedisulfonic acid (NDS)IBA 01/2014 - 12/2010
2	Prostaglandins FIBA 10/2012 - 01/2009
2	HT008-1IBA 08/2010 - 01/2008
2	Phosphotransferases (Kinase)IBA 07/2010 - 01/2006
2	Prostaglandin-E SynthasesIBA 06/2010 - 01/2008
2	Glucose (Dextrose)FDA LinkGeneric 03/2009 - 12/2008
2	Ginkgo biloba extract (Rokan)IBA 12/2008 - 09/2002
1	Dexmedetomidine FDA Link 04/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 09/2021
1	AlbuminsIBA 08/2021
1	Lipoproteins (Lipoprotein)IBA 01/2021

Therapy/Procedure

14	Therapeutics 02/2022 - 05/2003
2	Anesthesia 04/2022 - 01/2020
2	Length of Stay 01/2021 - 01/2018
2	Stroke Rehabilitation 01/2015 - 01/2015
2	Complementary Therapies (Alternative Medicine) 12/2013 - 09/2011
2	Oral Administration 12/2013 - 08/2010